1669 French explorer Robert de La Salle explores the Ohio River claiming the land for the French.
1748 A group of Virginians organized the Ohio Land Company with the goal of colonizing part of Ohio.
1761 A Morovian missionary build a log cabin near Bolivar.
1763 The British take over after the French and Indian War.
1782 The Gnadenhutten massacre occurs when 96 Lenape Indians are killed by an American militia.
1783 The United States takes control after the Revolutionary War.
1787 Ohio becomes part of the newly created Northwest Territory.
1788 The first permanent settlement is established in Marietta.
1789 The US army began construction of Fort Washington the site of present day Cincinnati.
1794 The Battle of Fallen Timbers is fought between a Confederacy of Native Americans in Ohio and the United States.
1796 Moses Cleveland founds Cleveland.
1803 Ohio becomes the 17th state.
1812 The War of 1812 is fought against the British and their Native American allies.
1816 Columbus becomes the capital.
1837 The Proctor & Gamble Company is established in Cincinnati.
1837 Oberlin College became the first to admit women.
1863 Confederate cavalry under the command of General Morgan raided Ohio, Morgan was captured near Salineville.
1870 John D. Rockfeller organized the Standard Oil Company in Cleveland.
1886 The American Federation of Trades and Labor was founded in Columbus.
1898 The Goodyear Tire and Rubber Company is established in Akron.
1955 The Ohio Turnpike opens.
1971 Four anti-war protesters were killed by the National Guard on the campus of Kent State.
1995 The Rock 'n Roll Hall of Fame museum opens in Cleveland.